[...] This priority relates to the evidence on the increase of chronic diseases and frailty amongst older people. In an ageing population such as Europe has today, tackling the challenges related to functional decline and loss of independence, namely through preventive measures that can contribute to the maintenance of the quality of life, are seen as a main area of concern and therefore a significant domain for further R&I initiatives. Besides, the need to move towards a proactive and preventive care (rather than continuing on a reactive care paradigm) has been highlighted and is nowadays being addressed by the healthcare systems of several European regions.